Description
Product Characteristics:
Aliases: CFL 2 antibody, CFL2 antibody, COF2_HUMAN antibody, Cofilin 2 muscle antibody, Cofilin antibody, Cofilin muscle antibody, Cofilin muscle isoform antibody, Cofilin-2 antibody, Cofilin2 antibody, muscle isoform antibody, NEM 7 antibody, NEM7 antibody
Target Information: This gene encodes an intracellular protein that is involved in the regulation of actin-filament dynamics. This protein is a major component of intranuclear and cytoplasmic actin rods. It can bind G- and F-actin in a 1:1 ratio of cofilin to actin, and it reversibly controls actin polymerization and depolymerization in a pH-dependent manner. Mutations in this gene cause nemaline myopathy type 7, a form of congenital myopathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2009]